Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538807 | 0.90 | KCNK3 (0.42) | KCNK3KCNK9RAB9AALDH1A1MEN1 | |
| SCHEMBL8539554 | 0.88 | CA1 (0.38) | KCNK3KCNK9RAB9AALDH1A1MEN1 | |
| SCHEMBL8540355 | 0.87 | KCNK3 (0.45) | KCNK3KCNK9RAB9AALDH1A1MEN1 | |
| SCHEMBL8536780 | 0.87 | MEN1 (0.39) | RAB9AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8542388 | 0.86 | ATIC (0.34) | RAB9AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8538564 | 0.85 | PARP1 (0.40) | KCNK3KCNK9RAB9AALDH1A1MEN1 | |
| SCHEMBL8542422 | 0.85 | PARP1 (0.36) | KCNK3KCNK9RAB9AALDH1A1MEN1 | |
| SCHEMBL8542364 | 0.81 | CES2 (0.47) | KCNK3KCNK9RAB9AALDH1A1MEN1 | |
| SCHEMBL8540372 | 0.81 | KCNK3 (0.37) | KCNK3KCNK9RAB9AALDH1A1MEN1 | |
| SCHEMBL8542528 | 0.81 | SMN1; SMN2 (0.34) | KCNK3KCNK9RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |