Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RHOC | P08134 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538589 | 0.74 | P2RX1 (0.41) | P2RX1AKR1C3AKR1C2KMT2AMAPT | |
| SCHEMBL8701056 | 0.69 | AKR1C3 (0.37) | P2RX1AKR1C3AKR1C2KMT2AMAPT | |
| SCHEMBL8538615 | 0.67 | RXFP1 (0.40) | MAOBKCNK3 | |
| SCHEMBL8538088 | 0.67 | P2RX1 (0.38) | P2RX1AKR1C3AKR1C2KMT2AMAPT | |
| SCHEMBL8542419 | 0.67 | PTGIR (0.38) | P2RX1AKR1C3AKR1C2MAPTLMNA | |
| SCHEMBL7498527 | 0.66 | HDAC3 (0.48) | P2RX1LMNARHOCRHOAMAOB | |
| SCHEMBL27496439 | 0.65 | CYP1A1 (0.51) | KMT2AMAPTLMNACYP1A2NPC1 | |
| SCHEMBL8542592 | 0.65 | P2RX1 (0.37) | P2RX1AKR1C3AKR1C2RHOCRHOA | |
| SCHEMBL8535813 | 0.64 | TAS2R14 (0.36) | P2RX1KMT2ARHOCRHOATRPA1 | |
| SCHEMBL19657964 | 0.64 | NPC1 (0.64) | P2RX1AKR1C3AKR1C2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |