Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RHOC | P08134 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538088 | 0.88 | P2RX1 (0.38) | P2RX1MAPTAKR1C3AKR1C2KMT2A | |
| SCHEMBL8538615 | 0.85 | RXFP1 (0.40) | KCNK3MAOB | |
| SCHEMBL8539554 | 0.83 | CA1 (0.38) | MAPTKMT2AKCNK3RAB9ANPC1 | |
| SCHEMBL8538094 | 0.76 | CES2 (0.42) | MAPTKMT2ALMNAKCNK3CYP1A2 | |
| SCHEMBL8538587 | 0.74 | P2RX1 (0.39) | P2RX1MAPTAKR1C3AKR1C2KMT2A | |
| SCHEMBL8542422 | 0.73 | PARP1 (0.36) | MAPTKMT2AKCNK3RAB9ANPC1 | |
| SCHEMBL8538564 | 0.73 | PARP1 (0.40) | MAPTKMT2ALMNAKCNK3RAB9A | |
| SCHEMBL8536787 | 0.73 | PARP1 (0.40) | MAPTKMT2ALMNAKCNK3RAB9A | |
| SCHEMBL8538385 | 0.72 | KCNK3 (0.43) | MAPTKMT2ALMNAKCNK3RAB9A | |
| SCHEMBL8542364 | 0.72 | CES2 (0.47) | MAPTKMT2AKCNK3CES2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |