Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538088 | 0.86 | P2RX1 (0.38) | RXFP1RORBRORC | |
| SCHEMBL8538589 | 0.85 | P2RX1 (0.41) | KCNK3MAOB | |
| SCHEMBL8540355 | 0.85 | KCNK3 (0.45) | KDM4EMAPK1KCNK3KCNK9 | |
| SCHEMBL8538385 | 0.72 | KCNK3 (0.43) | KCNK3KCNK9 | |
| SCHEMBL8542364 | 0.70 | CES2 (0.47) | RXFP1KCNK3KCNK9 | |
| SCHEMBL8538807 | 0.70 | KCNK3 (0.42) | KDM4EKCNK3KCNK9 | |
| SCHEMBL8539554 | 0.69 | CA1 (0.38) | KDM4EMAPK1KCNK3KCNK9 | |
| SCHEMBL8538610 | 0.69 | P2RX1 (0.36) | RXFP1KDM4EMAOB | |
| SCHEMBL8536780 | 0.69 | MEN1 (0.39) | MAPK1 | |
| SCHEMBL7508481 | 0.69 | ITGB3 (0.54) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |