Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RHOC | P08134 | 1/20 | 0.32 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531204 | 0.79 | RAB9A (0.35) | CYP1A2ALDH1A1CYP2C9MEN1POLB | |
| SCHEMBL8429205 | 0.72 | TACR1 (0.34) | TAS2R14ALDH1A1SMN1; SMN2TACR1PPARG | |
| SCHEMBL8429100 | 0.71 | BCHE (0.34) | TAS2R14CYP1A2TRPA1CYP3A4CYP2C9 | |
| SCHEMBL8432545 | 0.69 | BCHE (0.32) | TAS2R14SMN1; SMN2TACR1BCHE | |
| SCHEMBL8538589 | 0.66 | P2RX1 (0.41) | TAS2R14P2RX1CYP1A2TRPA1MEN1 | |
| SCHEMBL8538088 | 0.66 | P2RX1 (0.38) | TAS2R14P2RX1ALDH1A1MEN1KMT2A | |
| SCHEMBL8538615 | 0.66 | RXFP1 (0.40) | RXFP1 | |
| SCHEMBL7864673 | 0.66 | MAPT (0.42) | CYP1A2CYP3A4MEN1KMT2ATACR1 | |
| SCHEMBL8538587 | 0.64 | P2RX1 (0.39) | P2RX1CYP1A2TRPA1ALDH1A1KMT2A | |
| SCHEMBL8701056 | 0.64 | AKR1C3 (0.37) | P2RX1ALDH1A1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |