Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538467 | 0.88 | PPARG (0.37) | KDM4EALDH1A1L3MBTL1PTGS2HPGD | |
| SCHEMBL8341461 | 0.84 | ADORA3 (0.32) | KDM4EALDH1A1LMNAHTTRECQL | |
| SCHEMBL8538642 | 0.79 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNAHTTRECQL | |
| SCHEMBL8535968 | 0.79 | NPC1 (0.37) | SMN1; SMN2NPC1RAB9APTGS2 | |
| SCHEMBL8343243 | 0.75 | ADORA3 (0.34) | KDM4EALDH1A1LMNAHTTRECQL | |
| SCHEMBL11787842 | 0.75 | ALDH1A1 (0.45) | KDM4EALDH1A1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL6952530 | 0.73 | TNKS (0.53) | KDM4EALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8434646 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8538683 | 0.71 | KMT2A (0.39) | KDM4ELMNAHTTL3MBTL1NPC1 | |
| SCHEMBL8534397 | 0.70 | PPARG (0.34) | KDM4EALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |