Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266290 | 1.00 | LMNA (0.48) | LMNAMAPK1FABP4FABP5POLB | |
| SCHEMBL4029728 | 0.87 | CYSLTR2 (0.46) | LMNAMAPK1FABP4FABP5CYSLTR2 | |
| SCHEMBL31047124 | 0.83 | FABP4 (0.43) | LMNAMAPK1FABP4FABP5POLB | |
| SCHEMBL11502508 | 0.83 | CES2 (0.53) | LMNAMAPK1POLBALDH1A1CYP3A4 | |
| SCHEMBL6890650 | 0.83 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1 | |
| SCHEMBL8758384 | 0.82 | GABRA1 (0.39) | ALDH1A1GABRA1GABRB2CYP3A4CYP2D6 | |
| SCHEMBL8845975 | 0.82 | FABP4 (0.48) | LMNAMAPK1FABP4FABP5POLB | |
| SCHEMBL27771324 | 0.82 | LMNA (0.47) | LMNAMAPK1FABP4FABP5POLB | |
| SCHEMBL15375391 | 0.82 | FABP4 (0.59) | LMNAMAPK1FABP4FABP5GABRA1 | |
| SCHEMBL4239389 | 0.82 | FABP4 (0.48) | LMNAMAPK1FABP4FABP5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327766-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-12-02 | — | — | EP | disclosed |
| US-7261836-B2 | Chiral dopant with phenylethanediol functionality | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2007-08-28 | — | — | US | disclosed |
| US-20060022167-A1 | Chiral dopant with phenylethanediol functionality | KONINKLIJKE PHILIPS ELECTRONICS N.V. | 2006-02-02 | — | — | US | disclosed |
| EP-1519910-A1 | CHIRAL DOPANT WITH PHENYLETHANEDIOL FUNCTIONALITY | Koninklijke Philips Electronics N.V. (NL) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004002935-A1 | CHIRAL DOPANT WITH PHENYLETHANEDIOL FUNCTIONALITY | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060022167-A1 | Chiral dopant with phenylethanediol functionality | CRY2, CRY1, DDT | LMNA 1339/4885MAPK1 2407/4885FABP4 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.