Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537671 | 1.00 | TBXAS1 (0.45) | TBXAS1ALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL8538815 | 0.82 | TBXAS1 (0.40) | TBXAS1NAMPT | |
| SCHEMBL8535683 | 0.82 | TBXAS1 (0.45) | TBXAS1SMN1; SMN2HTR1ATERT | |
| SCHEMBL8536545 | 0.81 | TBXAS1 (0.40) | TBXAS1ALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL8535819 | 0.81 | TBXAS1 (0.48) | TBXAS1ALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL8535356 | 0.81 | TBXAS1 (0.48) | TBXAS1ALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL8536865 | 0.80 | TBXAS1 (0.46) | TBXAS1NAMPTTERT | |
| Hydrochloric Acid SCHEMBL8537563 | 0.77 | TBXAS1 (0.47) | TBXAS1HTTSMN1; SMN2CYP19A1TERT | |
| SCHEMBL8538995 | 0.76 | TBXAS1 (0.57) | TBXAS1ALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL8537670 | 0.76 | TBXAS1 (0.57) | TBXAS1ALDH1A1GAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |