Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537671 | 0.82 | TBXAS1 (0.45) | TBXAS1TERTHTR1ASMN1; SMN2 | |
| SCHEMBL8538862 | 0.82 | TBXAS1 (0.45) | TBXAS1TERTHTR1ASMN1; SMN2 | |
| SCHEMBL8536865 | 0.80 | TBXAS1 (0.46) | TBXAS1TERTHRH4TAAR1SLC6A4 | |
| SCHEMBL8540514 | 0.77 | TBXAS1 (0.44) | TBXAS1TERTTAAR1SLC6A4 | |
| SCHEMBL8536355 | 0.76 | TBXAS1 (0.57) | TBXAS1L3MBTL1 | |
| SCHEMBL8542267 | 0.75 | TBXAS1 (0.49) | TBXAS1TERTHRH4TAAR1HTR1A | |
| SCHEMBL27232031 | 0.73 | TBXAS1 (0.54) | TBXAS1TERTHRH4TAAR1HTR1A | |
| SCHEMBL4129898 | 0.73 | TBXAS1 (0.54) | TBXAS1TERTHRH4TAAR1HTR1A | |
| SCHEMBL503743 | 0.72 | TBXAS1 (0.69) | TBXAS1TERTTAAR1HTR1ASMN1; SMN2 | |
| SCHEMBL28062565 | 0.72 | TBXAS1 (0.69) | TBXAS1TERTTAAR1HTR1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |