Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538862 | 0.80 | TBXAS1 (0.45) | TBXAS1NAMPTTERT | |
| SCHEMBL8537671 | 0.80 | TBXAS1 (0.45) | TBXAS1NAMPTTERT | |
| SCHEMBL8535683 | 0.80 | TBXAS1 (0.45) | TBXAS1HRH4SLC6A4TERTTAAR1 | |
| SCHEMBL8538925 | 0.79 | TBXAS1 (0.46) | TBXAS1TERTTSHRMEN1CYP3A4 | |
| SCHEMBL8536914 | 0.78 | TBXAS1 (0.56) | TBXAS1NAMPT | |
| SCHEMBL8540333 | 0.76 | TBXAS1 (0.50) | TBXAS1NAMPTTAAR1 | |
| SCHEMBL8538489 | 0.73 | TBXAS1 (0.46) | TBXAS1NAMPT | |
| SCHEMBL4129898 | 0.71 | TBXAS1 (0.54) | TBXAS1HRH4TERTTAAR1 | |
| SCHEMBL27232031 | 0.71 | TBXAS1 (0.54) | TBXAS1HRH4TERTTAAR1 | |
| SCHEMBL503743 | 0.70 | TBXAS1 (0.69) | TBXAS1ADRA2BADRA2CTERTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |