Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL11816425 | 0.98 | ACHE (0.52) | ACHEKMT2AL3MBTL1TSHRGAA | |
| Azelaic Acid SCHEMBL29061113 | 0.98 | ACHE (0.52) | ACHEKMT2AL3MBTL1TSHRGAA | |
| Dodecanoate SCHEMBL11783043 | 0.91 | GPR84 (0.59) | KMT2ATSHRMEN1HSD17B10TDP1 | |
| Adipic Acid SCHEMBL27731397 | 0.89 | KMT2A (0.61) | KMT2AL3MBTL1TSHRGAAMEN1 | |
| Adipic Acid SCHEMBL3804252 | 0.89 | KMT2A (0.61) | KMT2AL3MBTL1TSHRGAAMEN1 | |
| Adipic Acid SCHEMBL29044502 | 0.89 | LMNA (0.58) | KMT2ATSHRGAAMEN1CASP1 | |
| Sebacic Acid SCHEMBL36102 | 0.87 | TSHR (0.60) | KMT2AL3MBTL1TSHRMEN1HSD17B10 | |
| Azelaic Acid SCHEMBL3807504 | 0.87 | TSHR (0.60) | KMT2AL3MBTL1TSHRMEN1HSD17B10 | |
| P-Xylene SCHEMBL36101 | 0.87 | TSHR (0.60) | KMT2AL3MBTL1TSHRMEN1HSD17B10 | |
| Sebacic Acid SCHEMBL28279615 | 0.87 | TSHR (0.60) | KMT2AL3MBTL1TSHRMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776933-B1 | Polybutene-1 resin composition and a method of accelerating the crystal transformation | NEW JAPAN CHEM CO LTD (JP) | 1999-08-04 | — | — | EP | disclosed |