Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.50 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL6544596 | 0.89 | LMNA (0.53) | LMNAKMT2AMEN1THRBMAPT | |
| Succinic Acid SCHEMBL27434396 | 0.89 | LMNA (0.53) | LMNAKMT2AMEN1THRBMAPT | |
| Adipic Acid SCHEMBL8539186 | 0.89 | ACHE (0.54) | LMNANFKB1TSHRPMP22KMT2A | |
| Azelaic Acid SCHEMBL29061113 | 0.87 | ACHE (0.52) | LMNANFKB1TSHRPMP22KMT2A | |
| Dodecanoate SCHEMBL8366235 | 0.87 | GPR84 (0.68) | LMNATSHRKMT2AHDAC11MEN1 | |
| SCHEMBL224789 | 0.87 | MAPT (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Sebacic Acid SCHEMBL11816425 | 0.87 | ACHE (0.52) | LMNANFKB1TSHRPMP22KMT2A | |
| Glutarate SCHEMBL10600593 | 0.86 | ALDH1A1 (0.56) | LMNATSHRKMT2AHDAC3HDAC4 | |
| SCHEMBL10987845 | 0.85 | MAPT (0.69) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4423281 | 0.85 | MAPT (0.69) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354829-B | Preparation method and application of pentyenediamine adipate | 中国科学院长春应用化学研究所 | 2025-02-07 | — | — | CN | disclosed |
| CN-116354829-A | Preparation method and application of pentyenediamine adipate | 中国科学院长春应用化学研究所 | 2023-06-30 | — | — | CN | disclosed |