Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543079 | 0.89 | BCHE (0.45) | BCHEACHEPTGDR2KDM4CQPCT | |
| SCHEMBL8543728 | 0.88 | BCHE (0.43) | BCHEACHEKDM4CQPCT | |
| SCHEMBL8544184 | 0.87 | BCHE (0.43) | BCHEACHEPTGDR2KDM4CQPCT | |
| SCHEMBL8539192 | 0.84 | ORAI1 (0.33) | BCHEACHEORAI1KDM4C | |
| SCHEMBL7616001 | 0.83 | BCHE (0.44) | BCHEACHEPTGDR2HPGDS | |
| SCHEMBL8541781 | 0.82 | BCHE (0.37) | BCHEACHEKDM4C | |
| SCHEMBL8539757 | 0.80 | ACHE (0.68) | BCHEACHEPTGDR2HPGDS | |
| SCHEMBL8543795 | 0.78 | BCHE (0.64) | BCHEACHE | |
| SCHEMBL8543195 | 0.77 | BCHE (0.61) | BCHEACHE | |
| SCHEMBL7620284 | 0.77 | BCHE (0.43) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |