SCHEMBL8539290

SCHEMBL8539290

CC(C)Sc1ncccc1F

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.47
FEN1 P39748 1/20 0.47
FFAR4 Q5NUL3 9/20 0.39
NPC1 O15118 2/20 0.35
GLA P06280 1/20 0.35
TSHR P16473 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 1/20 0.35
PPARG P37231 1/20 0.35
NCOA2 Q15596 1/20 0.35
NCOA1 Q15788 1/20 0.35
VCP P55072 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
RAB9A P51151 1/20 0.33
ATM Q13315 1/20 0.33
CTH P32929 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1583838 0.78 NOS3 (0.43) ALOX5APFEN1FFAR4NPC1L3MBTL1
SCHEMBL24645057 0.77
SCHEMBL31439210 0.77
SCHEMBL9023974 0.77 ALOX5AP (0.37) ALOX5APFEN1FFAR4
SCHEMBL5699951 0.76 PKM (0.38) ALOX5APFEN1FFAR4NPC1ALDH1A1
SCHEMBL5700020 0.76 ALOX5AP (0.38) ALOX5APFEN1FFAR4NPC1L3MBTL1
SCHEMBL6752009 0.76 ALDH1A1 (0.47) ALOX5APFEN1FFAR4NPC1L3MBTL1
SCHEMBL1583835 0.76 ALOX5AP (0.38) ALOX5APFEN1FFAR4NPC1ALDH1A1
SCHEMBL8538146 0.76 ALDH1A1 (0.39) ALOX5APFEN1FFAR4NPC1TSHR
SCHEMBL5700198 0.76 ALOX5AP (0.38) ALOX5APFEN1FFAR4NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0600836-B1 Selective herbicidal agent CIBA GEIGY AG (CH) 1998-08-05 EP disclosed
US-5612288-A PYRIDYLSULFONYLUREAS AS PLANT HERBICIDES CIBA GEIGY CORPORATION (US) 1997-03-18 US disclosed
US-5532203-A SULFONYLUREA MIXTURE CIBA-GEIGY CORPORATION (US) 1996-07-02 US disclosed
US-5410063-A Pyridin-2-yl-sulfonamides useful for the preparation of herbicidally active sulfonylureas CIBA-GEIGY CORPORATION (US) 1995-04-25 US disclosed
US-5352654-A Pre- and post-emergence herbicides, plant growth regulators CIBA-GEIGY CORPORATION (US) 1994-10-04 US disclosed
EP-0402316-B1 Sulphonylureas CIBA GEIGY AG (CH) 1994-09-14 EP disclosed
EP-0600836-A2 Selective herbicidal agent CIBA-GEIGY AG (CH) 1994-06-08 EP disclosed
EP-0402316-A1 Sulphonylureas CIBA-GEIGY AG (CH) 1990-12-12 EP disclosed