SCHEMBL9023974

SCHEMBL9023974

CC(C)Sc1ncccc1OC(F)F

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
TRPV4 Q9HBA0 1/20 0.36
FFAR4 Q5NUL3 4/20 0.34
DRD1 P21728 3/20 0.33
GRM4 Q14833 1/20 0.33
RXRA P19793 3/20 0.33
GRIN1 Q05586 3/20 0.33
GRIN2B Q13224 3/20 0.33
LMNA P02545 1/20 0.33
ADRA1A P35348 1/20 0.33
MET P08581 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
GRM5 P41594 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8534582 0.83 ALOX5AP (0.35) ALOX5APFEN1FFAR4METMEN1
SCHEMBL9023632 0.80 ALOX5AP (0.37) ALOX5APFEN1FFAR4DRD1MEN1
SCHEMBL8537336 0.80 FFAR4 (0.37) ALOX5APFEN1FFAR4LMNAMEN1
SCHEMBL8539290 0.77 ALOX5AP (0.47) ALOX5APFEN1FFAR4
SCHEMBL8535452 0.76 F9 (0.39) FFAR4LMNAKDM4EMEN1POLB
SCHEMBL31517933 0.73 TRPV4 (0.45) TRPV4DRD1GRM4ADRA1AKDM4E
Ammonia Solution, Strong SCHEMBL28510501 0.72 TRPV4 (0.44) TRPV4DRD1GRM4ADRA1AKDM4E
SCHEMBL29781487 0.71 TRPV4 (0.42) TRPV4GRM4RXRAGRIN1GRIN2B
SCHEMBL21801532 0.71 TRPV4 (0.42) TRPV4GRM4RXRAGRIN1GRIN2B
SCHEMBL1583838 0.71 NOS3 (0.43) ALOX5APFEN1FFAR4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0652708-B1 SELECTIVE HERBICIDAL COMPOSITION CIBA GEIGY AG (CH) 1996-04-17 EP disclosed
EP-0652708-A1 SELECTIVE HERBICIDAL COMPOSITION. CIBA GEIGY AG (CH) 1995-05-17 EP disclosed
US-5369083-A Herbicides CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed
EP-0582021-B1 Sulfonylureas as herbicides CIBA GEIGY AG (CH) 1994-07-13 EP disclosed
WO-1994003064-A1 SELECTIVE HERBICIDAL COMPOSITION CIBA-GEIGY AG (CH) 1994-02-17 WO disclosed
EP-0582021-A1 Sulfonylureas as herbicides CIBA-GEIGY AG (CH) 1994-02-09 EP disclosed