Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539522 | 0.91 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8539906 | 0.84 | TBXAS1 (0.65) | TBXAS1 | |
| SCHEMBL8543306 | 0.84 | TBXAS1 (0.85) | TBXAS1 | |
| SCHEMBL8538689 | 0.82 | TBXAS1 (0.84) | TBXAS1 | |
| SCHEMBL8539323 | 0.80 | TBXAS1 (0.61) | TBXAS1 | |
| SCHEMBL8581509 | 0.80 | TBXAS1 (0.61) | TBXAS1 | |
| SCHEMBL8543940 | 0.80 | TBXAS1 (0.65) | TBXAS1 | |
| SCHEMBL8637450 | 0.79 | TBXAS1 (0.59) | TBXAS1 | |
| SCHEMBL8539267 | 0.78 | TBXAS1 (0.79) | TBXAS1 | |
| SCHEMBL8539183 | 0.76 | HTR6 (0.52) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | claimed |
| WO-1995006046-A1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LIMITED (GB) | 1995-03-02 | — | — | WO | claimed |