Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539476 | 1.00 | QPCTL (0.44) | QPCTLLSSPDCD1CD274PRKAB2 | |
| SCHEMBL8538842 | 0.85 | LSS (0.48) | LSSPDCD1CD274PRKAB2PRKAG1 | |
| SCHEMBL8534755 | 0.84 | LSS (0.46) | LSSPDCD1CD274PRKAB2PRKAG1 | |
| SCHEMBL9589824 | 0.82 | EPHX2 (0.46) | LSSPDCD1CD274PRKAB2PRKAG1 | |
| SCHEMBL8534116 | 0.81 | LSS (0.49) | LSSHTR2AHTR2CHTR2BDRD3 | |
| SCHEMBL9523080 | 0.79 | MMP1 (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL8534724 | 0.79 | LSS (0.48) | LSSPDCD1CD274PRKAB2PRKAG1 | |
| SCHEMBL9523780 | 0.77 | LSS (0.55) | LSSHTR2AHTR2CHTR2BDRD3 | |
| SCHEMBL8537652 | 0.77 | CYP1A2 (0.47) | LSSPDCD1CD274PRKAB2PRKAG1 | |
| SCHEMBL8540635 | 0.77 | GPR119 (0.48) | LSSF10HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537201-B1 | 1-[4-(IMIDAZOL-1-YL)BENZOYL]PIPERIDINE DERIVATIVES AS ANTIARRHYTHMIC AGENTS | SCHERING AG (DE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0537201-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5189036-A | Cardiovascular agents; class III antiarrhythmic agents | SCHERING AG (DE) | 1993-02-23 | — | — | US | disclosed |
| WO-1991019709-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-12-26 | — | — | WO | disclosed |