Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 known ✓ | P02708 | 1/20 | 0.36 |
| ▸ | INMT | O95050 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539868 | 0.98 | INMT (0.56) | INMTRAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL14580451 | 0.92 | INMT (0.54) | INMTRAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL4974886 | 0.78 | MEN1 (0.39) | INMTRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL8673154 | 0.78 | INMT (0.50) | INMTRAB9ASMN1; SMN2LMNANPC1 | |
| Bromide SCHEMBL8674805 | 0.77 | INMT (0.48) | INMTRAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL11474728 | 0.74 | KMT2A (0.47) | INMTRAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL7735363 | 0.74 | — | — | |
| SCHEMBL8775918 | 0.73 | MGLL (0.43) | INMTRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL10975928 | 0.71 | — | — | |
| SCHEMBL9681470 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592676-B1 | IMINOSULFONYLUREA DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL IND LTD (JP) | 1998-09-30 | — | — | EP | disclosed |
| US-5686390-A | Iminosulfonylurea derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| US-5604179-A | PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| US-5500406-A | 1-AZOLYLIDENEIMINIOSULFONYL-3-PYRIMIDIN-2-YL UREAS; LOW DOSAGE; HIGH SELECTIVITY; CROPS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0592676-A1 | IMINOSULFONYLUREA DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1994-04-20 | — | — | EP | disclosed |