SCHEMBL8673154

SCHEMBL8673154

N=C1SCCN1CCCF

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
INMT O95050 6/20 0.50
CHRNA1 P02708 1/20 0.37
CHRNA7 P36544 1/20 0.37
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
NFKB1 P19838 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8674805 0.98 INMT (0.48) INMTCHRNA1CHRNA7KDM4ENPC1
SCHEMBL7735363 0.75
SCHEMBL9681470 0.68
Bromide SCHEMBL11738317 0.64 INMT (0.45) INMTCHRNA1CHRNA7KDM4ENPC1
SCHEMBL6686488 0.62 ALDH1A1 (0.30)
SCHEMBL7507814 0.60 CHRNA7 (0.68) INMTCHRNA1CHRNA7KDM4ENPC1
SCHEMBL8775918 0.59 MGLL (0.43) INMTNPC1MAPTRAB9ASMN1; SMN2
SCHEMBL11569068 0.57
SCHEMBL4071473 0.57 TERT (0.38)
SCHEMBL11623959 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9087261-A None JP disclosed
JP-9087261-A None JP disclosed
JP-7242665-A None JP disclosed
US-5763365-A CONTROLLING WEEDS IN SUGAR BEET FIELDS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-09 US disclosed
JP-H0987261-A PRODUCTION OF 3-(3-FLUOROPROPYL)-2-IMINOTHIAZOLINE NISSAN CHEM IND LTD 1997-03-31 JP disclosed
JP-H0987261-A PRODUCTION OF 3-(3-FLUOROPROPYL)-2-IMINOTHIAZOLINE NISSAN CHEM IND LTD 1997-03-31 JP disclosed
WO-1997000250-A1 PROCESS FOR PRODUCING 3-(3-FLUOROPROPYL)-2-IMINOTHIAZOLINE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-03 WO disclosed
WO-1997000250-A1 PROCESS FOR PRODUCING 3-(3-FLUOROPROPYL)-2-IMINOTHIAZOLINE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-03 WO disclosed
EP-0739893-A1 FLUOROPROPYLTHIAZOLINE DERIVATIVE AND HERBICIDE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-10-30 EP disclosed
JP-H07242665-A FLUOROPROPYLTHIAZOLINE DERIVATIVE AND HERBICIDE NISSAN CHEM IND LTD 1995-09-19 JP disclosed