Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 8/20 | 0.57 |
| ▸ | REN | P00797 | 2/20 | 0.51 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.46 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.46 |
| ▸ | PSMB3 | P49720 | 4/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.46 |
| ▸ | PSMA6 | P60900 | 4/20 | 0.46 |
| ▸ | PSMA8 | Q8TAA3 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534869 | 0.94 | CTSD (0.58) | CTSDREN | |
| SCHEMBL7270150 | 0.86 | HTT (0.51) | CTSDPSMB5 | |
| SCHEMBL7268430 | 0.85 | HTT (0.52) | CTSD | |
| SCHEMBL7279553 | 0.82 | HTT (0.48) | CTSD | |
| SCHEMBL7268478 | 0.82 | CTSD (0.54) | CTSD | |
| SCHEMBL8539753 | 0.81 | CTSD (0.39) | CTSDREN | |
| SCHEMBL6452185 | 0.81 | CTSB (0.51) | CTSDREN | |
| SCHEMBL6443882 | 0.81 | HTT (0.56) | — | |
| SCHEMBL6443877 | 0.81 | HTT (0.56) | — | |
| SCHEMBL6447441 | 0.80 | HTT (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |