Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 19/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875470 | 0.88 | DUT (0.48) | BCHE | |
| SCHEMBL8539901 | 0.84 | ALDH1A1 (0.59) | BCHEALDH1A1LMNAALBPOLB | |
| SCHEMBL8539898 | 0.84 | ALDH1A1 (0.59) | BCHEALDH1A1LMNAALBPOLB | |
| SCHEMBL741984 | 0.83 | POLB (0.47) | BCHEPOLB | |
| SCHEMBL6316914 | 0.76 | RNASE1 (0.42) | — | |
| SCHEMBL780047 | 0.75 | TK1 (0.49) | BCHE | |
| SCHEMBL25414279 | 0.75 | TYMS (0.44) | BLM | |
| SCHEMBL780058 | 0.74 | TYMP (0.44) | — | |
| SCHEMBL780214 | 0.73 | TYMP (0.43) | — | |
| SCHEMBL30976657 | 0.72 | HSP90AA1 (0.68) | BCHEALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394934-B2 | Method and process for synthesis of 2',3'-didehydro-2',3'-dideoxynucleosides | HUANG, ZHEN, DR. | 2013-03-12 | — | — | US | disclosed |
| US-20110105743-A1 | IMPROVED METHOD AND PROCESS FOR SYNTHESIS OF 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES | HUANG, ZHEN, DR. | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105743-A1 | IMPROVED METHOD AND PROCESS FOR SYNTHESIS OF 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES | DUT, DERA, UNG | BCHE 1249/4885ALDH1A1 1382/4885LMNA 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.