Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544650 | 0.76 | PARP1 (0.42) | RAB9AALDH1A1KCNK3KCNK9MEN1 | |
| SCHEMBL9304048 | 0.70 | SIRT2 (0.55) | RXFP1SIRT2KCNK3KCNK9MEN1 | |
| SCHEMBL8538801 | 0.70 | KDR (0.37) | RXFP1SIRT2KDRNPC1RAB9A | |
| SCHEMBL8538381 | 0.70 | PARP1 (0.38) | RXFP1KDRNPC1RAB9AALDH1A1 | |
| SCHEMBL8541181 | 0.69 | SIRT2 (0.52) | RXFP1SIRT2ALDH1A1HPGDKCNK3 | |
| SCHEMBL8539549 | 0.69 | KDM4E (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8431259 | 0.69 | RXFP1 (0.43) | RXFP1SIRT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8542380 | 0.69 | PARP1 (0.37) | RXFP1SIRT2KDRNPC1RAB9A | |
| SCHEMBL8541231 | 0.68 | PARP1 (0.40) | NPC1RAB9AALDH1A1HPGDKCNK3 | |
| SCHEMBL8542589 | 0.68 | KMT2A (0.43) | SIRT2NPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |