Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303308 | 0.88 | PTGES (0.56) | SIRT2MEN1KMT2APKMPTGES | |
| SCHEMBL9303936 | 0.87 | PTGES (0.52) | SIRT2MEN1KMT2APKMPTGES | |
| SCHEMBL9304320 | 0.86 | PLAU (0.50) | SIRT2MEN1KMT2APTGESKCNK3 | |
| SCHEMBL9302845 | 0.85 | PTGES (0.52) | SIRT2MEN1KMT2APTGESKCNK3 | |
| SCHEMBL9303615 | 0.85 | PDCD1 (0.55) | SIRT2F2PLGPLAUPLAT | |
| SCHEMBL9303020 | 0.84 | NR1H4 (0.53) | SIRT2PTGESRXFP1NR1H4F2 | |
| SCHEMBL9303041 | 0.83 | PLAU (0.61) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL8541181 | 0.82 | SIRT2 (0.52) | SIRT2MEN1KMT2APKMPTGES | |
| SCHEMBL14855807 | 0.81 | SIRT2 (0.78) | SIRT2MEN1KMT2APKMRXFP1 | |
| SCHEMBL9304321 | 0.81 | PLAU (0.50) | SIRT2MEN1KMT2APTGESF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |