Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542018 | 0.86 | CYP1A2 (0.45) | PARP1PARP10PARP15PARP14KCNK3 | |
| SCHEMBL8542589 | 0.83 | KMT2A (0.43) | PARP1PARP10PARP15PARP14KMT2A | |
| SCHEMBL8541231 | 0.79 | PARP1 (0.40) | PARP1PARP10PARP15PARP14KCNK3 | |
| SCHEMBL5354517 | 0.76 | L3MBTL1 (0.60) | KCNK3KCNK9MEN1KMT2AALDH1A1 | |
| SCHEMBL1185244 | 0.76 | KMT2A (0.58) | PARP1PARP10PARP15MEN1KMT2A | |
| SCHEMBL8540211 | 0.76 | RXFP1 (0.44) | KCNK3KCNK9MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3839558 | 0.74 | KMT2A (0.57) | PARP1PARP10PARP15MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29568124 | 0.74 | KMT2A (0.57) | PARP1PARP10PARP15MEN1KMT2A | |
| SCHEMBL895690 | 0.74 | MEN1 (0.63) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL27419737 | 0.73 | PLK4 (0.44) | PARP1PARP10PARP15PARP14KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |