Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506955 | 0.92 | KMT2A (0.50) | KMT2AMAPTNPC1PKMKCNK3 | |
| SCHEMBL7497380 | 0.92 | KMT2A (0.50) | KMT2AMAPTNPC1PKMKCNK3 | |
| SCHEMBL8539479 | 0.90 | ALDH1A1 (0.46) | KDM4EKMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL8538091 | 0.90 | KMT2A (0.46) | KDM4EKMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL8542887 | 0.90 | KCNK3 (0.46) | KDM4EKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8541777 | 0.89 | ALDH1A1 (0.42) | KDM4EKMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL8539492 | 0.87 | MAPT (0.49) | KMT2AMAPTALDH1A1RAB9APKM | |
| SCHEMBL8540369 | 0.84 | KDM4E (0.41) | KDM4EKMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL8544854 | 0.83 | RAB9A (0.42) | KMT2AALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL8538573 | 0.80 | EPHX2 (0.41) | KDM4EKMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |