SCHEMBL8540386

SCHEMBL8540386

COc1ccc(C(c2cccs2)c2cccs2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.46
AHR P35869 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
TP53 P04637 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ACHE P22303 1/20 0.40
MAPT P10636 3/20 0.40
GFER P55789 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2433699 0.91 ACP3 (0.46) SLC2A1AHRTP53SMN1; SMN2L3MBTL1
SCHEMBL14629742 0.83 SLC2A1 (0.40) SLC2A1AHRTP53NPC1RAB9A
SCHEMBL14629738 0.82 CNR2 (0.52) TP53NPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL28574394 0.81 MEN1 (0.48) TP53NPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL14632125 0.78 ALDH1A1 (0.33) SLC2A1AHRTP53NPC1RAB9A
SCHEMBL31065464 0.76 MAPT (0.57) AHRTP53NPC1RAB9ATSHR
SCHEMBL28096032 0.75 L3MBTL1 (0.47) TP53NPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL16859725 0.75 SLC2A1 (0.71) SLC2A1CA12CA1CA2CA7
SCHEMBL41022 0.75 SLC2A1 (0.71) SLC2A1CA12CA1CA2CA7
SCHEMBL15003945 0.73 ALDH1A1 (0.57) TP53NPC1RAB9ASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5827501-A INERT TRIARYLMETHYL FREE RADICAL CONTRAST AGENTS FOR ELECTRON SPIN RESONANCE (ESR) ENHANCED MAGNETIC RESONANCE (EMR) IMAGING NYCOMED IMAGING AS (NO) 1998-10-27 US disclosed
US-5599522-A CONTRAST ENHANCING AGENTS NYCOMED IMAGING AS (NO) 1997-02-04 US disclosed
EP-0515458-B1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI NYCOMED INNOVATION AB (SE) 1995-08-23 EP disclosed
EP-0515458-A1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI. HAFSLUND NYCOMED INNOVATION (SE) 1992-12-02 EP disclosed
WO-1991012024-A1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI HAFSLUND NYCOMED INNOVATION AB (SE) 1991-08-22 WO disclosed