Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27482821 | 0.86 | POLB (0.45) | ALDH1A1MEN1KMT2ANPSR1HPGD | |
| SCHEMBL13236796 | 0.85 | ALOX15 (0.44) | L3MBTL1FFAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL28096025 | 0.84 | SLC6A3 (0.41) | FFAR1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL628797 | 0.81 | LMNA (0.56) | L3MBTL1FFAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL2889581 | 0.80 | TDP1 (0.60) | L3MBTL1MEN1KMT2ANPSR1HPGD | |
| SCHEMBL2889577 | 0.80 | TDP1 (0.60) | L3MBTL1MEN1KMT2ANPSR1HPGD | |
| SCHEMBL7279728 | 0.77 | KCNA5 (0.44) | ALDH1A1KMT2AHPGDPOLBNPC1 | |
| SCHEMBL13118146 | 0.76 | AHR (0.43) | L3MBTL1FFAR1NPSR1HPGDNPC1 | |
| SCHEMBL13318255 | 0.76 | AHR (0.43) | L3MBTL1FFAR1NPSR1HPGDNPC1 | |
| SCHEMBL13318256 | 0.76 | AHR (0.43) | L3MBTL1FFAR1NPSR1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105924425-A | Preparation method of dihydrothiochroman derivative | 浙江师范大学 | 2016-09-07 | — | — | CN | disclosed |