Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432606 | 0.77 | GRIN1 (0.33) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL30500255 | 0.73 | HSD17B10 (0.40) | CHRM3KDM4ELMNACYP1A2ALDH1A1 | |
| SCHEMBL30500197 | 0.72 | ALDH1A1 (0.40) | KDM4ECYP1A2ALDH1A1HTTHPGD | |
| SCHEMBL1701402 | 0.71 | KDM4E (0.41) | KDM4E | |
| SCHEMBL14157582 | 0.68 | CYP19A1 (0.38) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL4064144 | 0.68 | OPRM1 (0.55) | GRIN1GRIN2AGRIN2BCHRM2CHRM4 | |
| SCHEMBL765328 | 0.68 | OPRM1 (0.55) | GRIN1GRIN2AGRIN2BCHRM2CHRM4 | |
| SCHEMBL31221485 | 0.68 | OPRM1 (0.55) | GRIN1GRIN2AGRIN2BCHRM2CHRM4 | |
| SCHEMBL15976741 | 0.68 | CHRM2 (0.39) | GRIN1GRIN2AGRIN2BCHRM2CHRM4 | |
| SCHEMBL10957293 | 0.68 | SLC6A4 (0.34) | GRIN1GRIN2AGRIN2BLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540697-B1 | SULFONYLUREAS | CIBA GEIGY AG (CH) | 1998-06-03 | — | — | EP | disclosed |
| US-5625071-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5403814-A | Preemergence and postemergence herbicides | CIBA-GEIGY CORPORATION (US) | 1995-04-04 | — | — | US | disclosed |
| EP-0540697-A1 | NOVEL SULFONYLUREAS | Novartis AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992016522-A1 | NOVEL SULFONYLUREAS | CIBA-GEIGY AG (CH) | 1992-10-01 | — | — | WO | disclosed |