Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TST | Q16762 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12981303 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL17378377 | 0.82 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1896384 | 0.82 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL16473176 | 0.82 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1896385 | 0.82 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL23192305 | 0.82 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL25891630 | 0.78 | ALDH1A1 (0.47) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL6897254 | 0.76 | VDR (0.45) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL20848316 | 0.76 | VDR (0.45) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL9243595 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776921-A | STEROIDS AND DERIVATIVES FOR IMMUNOLOGY AND CELL PROLIFERATION AND DIFFERENTIATION | GATES STEPHEN (US) | 1998-07-07 | — | — | US | disclosed |