Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542491 | 0.81 | PSEN1 (0.50) | CYP3A4CYP2C19HTTL3MBTL1POLB | |
| SCHEMBL8540088 | 0.77 | PSEN1 (0.46) | HPGDALDH1A1HSD17B10MAPTCYP3A4 | |
| SCHEMBL31285478 | 0.75 | ENPP2 (0.36) | KIF11NPC1RAB9ARXRAENPP2 | |
| SCHEMBL8540926 | 0.75 | KIF11 (0.40) | KIF11KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL8545653 | 0.75 | KDM4E (0.44) | KIF11KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL5751159 | 0.74 | ACSS2 (0.39) | KDM4ENPC1RAB9ASIRT2 | |
| SCHEMBL13053078 | 0.73 | CYP11B1 (0.42) | TSHRCYP3A4CYP2C19ENPP2MEN1 | |
| SCHEMBL2918068 | 0.73 | CYP19A1 (0.39) | KIF11TSHRCYP3A4CYP2C19MEN1 | |
| SCHEMBL31359426 | 0.73 | CYP2C19 (0.43) | KIF11KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL3755263 | 0.73 | CYP2C19 (0.43) | KIF11KDM4EHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820989-A1 | IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |