Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | GLS | O94925 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | GPR6 | P46095 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809169 | 1.00 | FAAH (0.59) | FAAHCHRM4GLSNSD2RORC | |
| SCHEMBL1632572 | 0.93 | FAAH (0.53) | FAAHCHRM4GLSNSD2RORC | |
| SCHEMBL29121436 | 0.89 | KCNH2 (0.54) | FAAHCHRM4NSD2DRD2DRD3 | |
| SCHEMBL23334597 | 0.88 | GLS (0.49) | FAAHCHRM4GLSNSD2CHRM2 | |
| SCHEMBL1066770 | 0.85 | CYP3A4 (0.60) | FAAHNSD2GPR119HRH1 | |
| SCHEMBL3912590 | 0.84 | FAAH (0.44) | FAAHCHRM4MGLLGPR119 | |
| SCHEMBL23552038 | 0.83 | VEGFA (0.48) | FAAHCHRM4NSD2GPR6GPR119 | |
| SCHEMBL2194827 | 0.83 | KDM1A (0.57) | CHRM4GLSCHRM2CHRM1CHRM3 | |
| SCHEMBL4837787 | 0.83 | GLS (0.54) | CHRM4GLSCHRM2CHRM1CHRM3 | |
| SCHEMBL8540779 | 0.83 | ALDH1A1 (0.63) | FAAHGLSCHRM2CHRM3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817489-A | BACTERICIDES, OR CHEMICAL INTERMEDIATES THEREOF; DRUG LIBRARIES | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | claimed |
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |