Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644988 | 0.89 | PNMT (0.43) | ENPP2EPHX2SRD5A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL30927569 | 0.86 | SRD5A2 (0.45) | ENPP2SRD5A2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8472728 | 0.81 | PNMT (0.44) | ENPP2EPHX2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29222741 | 0.81 | NPC1 (0.48) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL6502789 | 0.81 | PNMT (0.54) | ENPP2EPHX2SRD5A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7428664 | 0.80 | ENPP2 (0.49) | ENPP2SMN1; SMN2ALDH1A1NR1H4NPC1 | |
| SCHEMBL31633620 | 0.80 | PNMT (0.53) | ENPP2EPHX2SRD5A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL27703872 | 0.79 | PNMT (0.51) | ENPP2EPHX2SRD5A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL27548469 | 0.79 | PPARG (0.54) | SRD5A2HTTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2489956 | 0.78 | EPHX1 (0.47) | EPHX2SRD5A2KMT2ANR1H4PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824538-A1 | SACCHAROPEPTIDES AND DERIVATIVES THEREOF | GLYCOMED INCORPORATED (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035700-A9 | SACCHAROPEPTIDES AND DERIVATIVES THEREOF | — | 1997-02-13 | — | — | WO | disclosed |
| WO-1996035700-A1 | SACCHAROPEPTIDES AND DERIVATIVES THEREOF | GLYCOMED INCORPORATED (US) | 1996-11-14 | — | — | WO | disclosed |