SCHEMBL8541015

SCHEMBL8541015

O=C(Nc1ccccc1C(=O)O)OCc1ccc2c(c1)-c1ccccc1C2

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.51
TSHR P16473 2/20 0.48
CYP2C9 P11712 1/20 0.48
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HCAR2 Q8TDS4 7/20 0.43
CASP3 P42574 1/20 0.43
SRD5A2 P31213 1/20 0.43
CYP1A2 P05177 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
CYP3A4 P08684 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29222741 0.79 NPC1 (0.48) PPARGTSHRCYP2C9NPC1RAB9A
SCHEMBL8541037 0.79 CYP2C9 (0.53) PPARGTSHRCYP2C9NPC1RAB9A
SCHEMBL2233522 0.78 NPC1 (0.69) NPC1RAB9ACASP3ALDH1A1PTPN1
SCHEMBL9986247 0.76 SRD5A2 (0.45) PPARGTSHRNPC1RAB9ACASP3
SCHEMBL9986249 0.76 HTR2C (0.49) PPARGTSHRNPC1RAB9ACASP3
SCHEMBL5055502 0.76 NPC1 (0.58) NPC1RAB9AHCAR2ALDH1A1PTPN1
SCHEMBL8338982 0.76 SLC1A3 (0.61) TSHRCYP2C9NPC1RAB9ACASP3
SCHEMBL5060744 0.75 NPC1 (0.54) TSHRNPC1RAB9AALDH1A1CYP3A4
SCHEMBL22497489 0.75 KDM4E (0.61) NPC1RAB9AHCAR2CASP3CYP1A2
SCHEMBL22497537 0.74 TRPV1 (0.58) PPARGCYP2C9NPC1RAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0824538-A1 SACCHAROPEPTIDES AND DERIVATIVES THEREOF GLYCOMED INCORPORATED (US) 1998-02-25 EP disclosed
WO-1996035700-A9 SACCHAROPEPTIDES AND DERIVATIVES THEREOF 1997-02-13 WO disclosed
WO-1996035700-A1 SACCHAROPEPTIDES AND DERIVATIVES THEREOF GLYCOMED INCORPORATED (US) 1996-11-14 WO disclosed