Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986249 | 0.85 | HTR2C (0.49) | SRD5A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7384746 | 0.79 | ALDH1A1 (0.51) | SRD5A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1310566 | 0.79 | GPR84 (0.44) | SRD5A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8541015 | 0.76 | PPARG (0.51) | SRD5A2RAB9ACASP3CYP1A2NPC1 | |
| SCHEMBL1307495 | 0.76 | ALDH1A1 (0.41) | SRD5A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3452644 | 0.75 | SRD5A2 (0.54) | SRD5A2HTR2CHTR2BCYP1A2ADRA2A | |
| SCHEMBL7342872 | 0.75 | RAB9A (0.44) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL3453563 | 0.74 | NPC1 (0.48) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL896998 | 0.73 | PNMT (0.54) | SRD5A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7190397 | 0.73 | GPR84 (0.52) | SRD5A2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2392400-A2 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2011-12-07 | — | — | EP | disclosed |