Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986247 | 0.85 | SRD5A2 (0.45) | HTR2CHTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL7384746 | 0.79 | ALDH1A1 (0.51) | HTR2CHTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL15084997 | 0.77 | MAPT (0.53) | HTR2BHTR7RAB9ANPC1MAPT | |
| Fluorene SCHEMBL2673075 | 0.76 | GABRP (0.56) | HTR2CHTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL8541015 | 0.76 | PPARG (0.51) | SRD5A2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL1307495 | 0.76 | ALDH1A1 (0.41) | HTR2CHTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL1310566 | 0.76 | GPR84 (0.44) | HTR2CHTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL3452644 | 0.75 | SRD5A2 (0.54) | HTR2CHTR2BSRD5A2ALDH1A1KDM4E | |
| SCHEMBL7342872 | 0.75 | RAB9A (0.44) | HTR2CHTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL29699123 | 0.74 | SRD5A2 (0.50) | HTR2CHTR2BDRD2ADRA1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105640882-A | Cabazitaxel micelle drug loading system and preparation method and application thereof | 姚俊华 | 2016-06-08 | — | — | CN | claimed |
| CN-105399931-A | Amphiphilic block copolymer and preparation method and application thereof | YAO JUNHUA | 2016-03-16 | — | — | CN | claimed |
| CN-105399938-A | Preparation method and application of amphiphilic block copolymer and micelle thereof | YAO JUNHUA | 2016-03-16 | — | — | CN | claimed |
| CN-105395481-A | Curcumin-containing polymer micelle drug delivery system and preparation method and application thereof | YAO JUNHUA | 2016-03-16 | — | — | CN | claimed |
| CN-105310981-A | Docetaxel micelle drug loading system and preparation method and application thereof | YAO JUNHUA | 2016-02-10 | — | — | CN | claimed |
| CN-105287377-A | Paclitaxel polymer micelle drug-loading system and preparation method and application thereof | YAO JUNHUA | 2016-02-03 | — | — | CN | claimed |
| CN-107629016-B | Evans blue complex and preparation method and application thereof | 莎穆(上海)生物科技有限公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-105399938-B | Preparation method and application of amphiphilic block copolymer and micelle thereof | 江苏万高药业股份有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-105399931-B | Amphiphilic block copolymer and preparation method and application thereof | 江苏万高药业股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-105640882-A | Cabazitaxel micelle drug loading system and preparation method and application thereof | 姚俊华 | 2016-06-08 | — | — | CN | disclosed |
| CN-105399931-A | Amphiphilic block copolymer and preparation method and application thereof | YAO JUNHUA | 2016-03-16 | — | — | CN | disclosed |
| CN-105399938-A | Preparation method and application of amphiphilic block copolymer and micelle thereof | YAO JUNHUA | 2016-03-16 | — | — | CN | disclosed |
| CN-105395481-A | Curcumin-containing polymer micelle drug delivery system and preparation method and application thereof | YAO JUNHUA | 2016-03-16 | — | — | CN | disclosed |
| CN-105310981-A | Docetaxel micelle drug loading system and preparation method and application thereof | YAO JUNHUA | 2016-02-10 | — | — | CN | disclosed |
| CN-105287377-A | Paclitaxel polymer micelle drug-loading system and preparation method and application thereof | YAO JUNHUA | 2016-02-03 | — | — | CN | disclosed |
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2392400-A2 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2011-12-07 | — | — | EP | disclosed |