Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541109 | 0.87 | RAB9A (0.67) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL9383475 | 0.85 | LMNA (0.58) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL9383480 | 0.84 | RAB9A (0.55) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8548873 | 0.82 | RAB9A (0.60) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8548739 | 0.81 | RAB9A (0.69) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8545058 | 0.81 | RAB9A (0.80) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8540692 | 0.81 | RAB9A (0.65) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8543212 | 0.81 | RAB9A (0.51) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8546894 | 0.80 | LMNA (0.64) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8546815 | 0.80 | RAB9A (0.69) | RAB9ANPC1TSHRL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9072301-B2 | Fungicidal pyrimidine compounds | BASF SE (DE) | 2015-07-07 | — | — | US | disclosed |
| US-20140371065-A1 | Fungicidal Pyrimidine Compounds | BASF SE (DE) | 2014-12-18 | — | — | US | disclosed |
| EP-2809659-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013113715-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2013-08-08 | — | — | WO | disclosed |
| US-5326766-A | Fungicide, nematocide, insecticide, miticide | DOWELANCO | 1994-07-05 | — | — | US | disclosed |
| WO-1994004526-A1 | 4-[2-(4-(2-PYRIDINYLOXY)PHENYL)ETHOXY]-QUINAZOLINE AND ANALOGUES THEREOF | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1994004526-A1 | 4-[2-(4-(2-PYRIDINYLOXY)PHENYL)ETHOXY]-QUINAZOLINE AND ANALOGUES THEREOF | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1994004526-A1 | 4-[2-(4-(2-PYRIDINYLOXY)PHENYL)ETHOXY]-QUINAZOLINE AND ANALOGUES THEREOF | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371065-A1 | Fungicidal Pyrimidine Compounds | DPM1, DPYD, TYMP | RAB9A 3989/4885NPC1 1515/4885TSHR 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.