Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.39 |
| ▸ | AR | P10275 | 9/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540866 | 0.82 | CYP19A1 (0.35) | PGRARCYP3A4STSESR1 | |
| SCHEMBL8541045 | 0.81 | PGR (0.59) | PGRARNR3C1CYP3A4ESR1 | |
| SCHEMBL22861553 | 0.73 | NR3C1 (0.71) | PGRARNR3C1CYP3A4 | |
| SCHEMBL21143400 | 0.72 | NR3C1 (0.72) | PGRARNR3C1CYP3A4 | |
| SCHEMBL21143415 | 0.72 | ESR1 (0.37) | PGRARNR3C1CYP3A4STS | |
| SCHEMBL20048226 | 0.72 | ESR1 (0.37) | PGRARNR3C1CYP3A4STS | |
| SCHEMBL20048225 | 0.72 | ESR1 (0.37) | PGRARNR3C1CYP3A4STS | |
| SCHEMBL21470229 | 0.71 | NR3C1 (0.73) | PGRARNR3C1CYP3A4 | |
| SCHEMBL9019868 | 0.71 | PDK1 (0.36) | PGRARNR3C1CYP3A4STS | |
| SCHEMBL9019805 | 0.71 | PGR (0.35) | PGRARNR3C1CYP3A4STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000051623-A2 | INHIBITORS OF SERINE PROTEASE ACTIVITY, METHODS AND COMPOSITIONS FOR TREATMENT OF NITRIC OXIDE-INDUCED CLINICAL CONDITIONS | THE TRUSTEES OF UNIVERSITY TECHNOLOGY CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-0404283-B1 | 11-Beta-aryl-4-estrene, method for its production and its use as a medicine | SCHERING AG (DE) | 1996-05-08 | — | — | EP | disclosed |
| EP-0404283-A2 | 11-Beta-aryl-4-estrene, method for its production and its use as a medicine | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-12-27 | — | — | EP | disclosed |