Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10225804 | 0.89 | MEN1 (0.38) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL91944 | 0.82 | MEN1 (0.37) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL10225788 | 0.82 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL84822 | 0.82 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL85236 | 0.82 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL85480 | 0.80 | MAPT (0.34) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL10225812 | 0.80 | MAPT (0.34) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL14592457 | 0.78 | ITGB1 (0.38) | MAPTALDH1A1NPSR1POLBSMN1; SMN2 | |
| SCHEMBL85318 | 0.76 | MAPT (0.35) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL85319 | 0.74 | PKM (0.37) | MEN1KMT2AMAPTALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129366-B2 | VLA-4 inhibitory drug | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090233901-A1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233901-A1 | VLA-4 INHIBITORY DRUG | VCAM1, ITGB4, ITGA4 | MEN1 4226/4885KMT2A 881/4885MAPT 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.