Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA4 | P22748 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327957 | 0.92 | MEN1 (0.58) | F2MEN1KMT2APOLBCA12 | |
| SCHEMBL7329319 | 0.87 | F2 (0.54) | F2MEN1KMT2APOLBHTT | |
| SCHEMBL7335466 | 0.85 | ESR1 (0.59) | KMT2ACA12CA1CA2CA4 | |
| SCHEMBL14878181 | 0.83 | F2 (0.67) | F2MEN1KMT2APOLBCA12 | |
| SCHEMBL7328822 | 0.83 | ESR1 (0.54) | F2KMT2APOLBCA12CA1 | |
| SCHEMBL7324331 | 0.81 | CA12 (0.61) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10186896 | 0.80 | PGR (0.70) | F2CA12CA9SMN1; SMN2NR1H3 | |
| SCHEMBL7996336 | 0.80 | LMNA (0.63) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL29955055 | 0.80 | LMNA (0.63) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL7331867 | 0.80 | KMT2A (0.57) | F2MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |