SCHEMBL85427

SCHEMBL85427

COCCCN1CCOCC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.56
ALDH1A1 P00352 3/20 0.56
MAPK1 P28482 2/20 0.56
CYP1A2 P05177 1/20 0.56
CHRM2 P08172 1/20 0.56
CHRM1 P11229 1/20 0.56
HTR2A P28223 1/20 0.56
SCN1A P35498 1/20 0.56
HTR2B P41595 1/20 0.56
KCNH2 Q12809 1/20 0.56
SCN2A Q99250 1/20 0.56
SIGMAR1 Q99720 1/20 0.56
SCN3A Q9NY46 1/20 0.56
USP2 O75604 1/20 0.54
LMNA P02545 1/20 0.54
CYP2D6 P10635 2/20 0.54
TSHR P16473 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
KEAP1 Q14145 1/20 0.54
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259408 0.94 ALDH1A1 (0.53) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL13845059 0.92 HRH3 (0.50) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL20332795 0.92 ALDH1A1 (0.50) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL24389176 0.92 ALDH1A1 (0.55) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL10926726 0.92 ALDH1A1 (0.55) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL23137450 0.91 ALDH1A1 (0.49) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL20332380 0.88 ALDH1A1 (0.50) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL20332826 0.88 TDP1 (0.47) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL21148408 0.88 ALDH1A1 (0.50) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL81823 0.86 TDP1 (0.56) HRH3ALDH1A1MAPK1CYP1A2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107743502-B Curing composition 爱客多有限公司 2020-08-28 CN claimed
US-9926404-B2 Curing compositions AQDOT LIMITED (GB) 2018-03-27 US claimed
CN-107743502-A Solidification composition filling 爱客多有限公司 2018-02-27 CN claimed
EP-3095804-B1 CURING COMPOSITIONS AQDOT LTD (GB) 2017-09-27 EP claimed
US-20160340467-A1 CURING COMPOSITIONS AQDOT LIMITED (GB) 2016-11-24 US claimed
WO-2016185209-A1 CURING COMPOSITIONS AQDOT LIMITED (GB) 2016-11-24 WO claimed
EP-3095804-A1 CURING COMPOSITIONS Aqdot Ltd (GB) 2016-11-23 EP claimed
CN-101173023-A Method for regulating conjugated diene hydrocarbon and monovinylarene copolymer structure UNIV DALIAN MARITIME (CN) 2008-05-07 CN claimed
EP-0154669-A1 Catalyst for urethane foam blown with carboxylic acids ABBOTT LABORATORIES (US) 1985-09-18 EP claimed
EP-0144573-A2 Catalyst system for the production of polyurethanes AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-06-19 EP claimed
US-4500654-A N-SUBSTITUTED ALKOXYALKYL PIPERAZINE ABBOTT LABORATORIES (US) 1985-02-19 US claimed
US-4473666-A A DIALKYLCYCLOHEXYLAMINE AND AN N-SUBSTITUTED ALKOXYALKYL PIPERAZINE ABBOTT LABORATORIES (US) 1984-09-25 US claimed
US-4326042-A Morpholine and piperazine derivatives in a catalyst system for polyester-based polyurethane foams TEXACO INC. (US) 1982-04-20 US claimed
EP-4389751-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Kumquat Biosciences Inc. (US) 2024-06-26 EP disclosed
US-11834463-B2 High affinity macrocyclic FKB51-inhibitors for treatment of psychiatric disorders Technische Universität Darmstadt (DE) 2023-12-05 US disclosed
US-11834463-B2 High affinity macrocyclic FKB51-inhibitors for treatment of psychiatric disorders Technische Universität Darmstadt (DE) 2023-12-05 US disclosed
EP-0082597-A1 Catalyst-solvent system for polyurethane foams TEXACO DEVELOPMENT CORPORATION (US) 1983-06-29 EP disclosed
US-4376832-A Catalyst-solvent system for polyester-based polyurethane foams comprising N-butylmorpholine and N,N'-dimethylpiperazine and the solvent TEXACO INC. (US) 1983-03-15 US disclosed
US-4326042-A Morpholine and piperazine derivatives in a catalyst system for polyester-based polyurethane foams TEXACO INC. (US) 1982-04-20 US disclosed
US-4326042-A Morpholine and piperazine derivatives in a catalyst system for polyester-based polyurethane foams TEXACO INC. (US) 1982-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834463-B2 High affinity macrocyclic FKB51-inhibitors for treatment of psychiatric disorders FKBP1B, FKBP5, FKBP1A HRH3 2987/4885ALDH1A1 4075/4885MAPK1 1377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.