Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 7/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237220 | 0.75 | KMT2A (0.47) | TSHRNMT1FDPSBRD4 | |
| SCHEMBL7940932 | 0.75 | QPCT (0.48) | HRH3QPCT | |
| SCHEMBL7931377 | 0.73 | SLC6A4 (0.39) | NMT1BRD4HRH3SLC6A4MERTK | |
| SCHEMBL8539959 | 0.72 | LMNA (0.76) | LMNATSHRHTTNPSR1SLC6A4 | |
| SCHEMBL3520240 | 0.72 | SRC (0.38) | LMNATSHRHTTNPSR1NR3C1 | |
| SCHEMBL18256012 | 0.71 | CYP11B2 (0.44) | LMNATSHRHTTNPSR1FDPS | |
| SCHEMBL20011450 | 0.71 | CYP11B2 (0.41) | LMNATSHRHTTNPSR1FDPS | |
| SCHEMBL10417634 | 0.70 | BRD4 (0.43) | NR3C1BRD4HRH3SLC6A4GNAO1 | |
| SCHEMBL3516432 | 0.69 | ADORA2A (0.56) | LMNA | |
| SCHEMBL10417947 | 0.69 | SMN1; SMN2 (0.47) | NMT1NR3C1BRD4HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |