Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 5/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | HCK | P08631 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.34 |
| ▸ | PRKDC | P78527 | 3/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13732328 | 0.81 | SRC (0.33) | SRCABL1LMNATSHRHTT | |
| SCHEMBL3519511 | 0.79 | TGFBR1 (0.39) | — | |
| SCHEMBL3516432 | 0.76 | ADORA2A (0.56) | LMNAPI4KB | |
| SCHEMBL9108201 | 0.73 | ADORA2A (0.36) | LMNAPI4KB | |
| 3-Propyladenine SCHEMBL15756434 | 0.72 | ADORA2A (0.53) | LMNAPI4KB | |
| SCHEMBL8543711 | 0.72 | LMNA (0.39) | TLR7LMNATSHRHTTNPSR1 | |
| SCHEMBL10267988 | 0.71 | SRC (0.46) | SRCHSP90AA1HSP90AB1ABL1PIK3CD | |
| SCHEMBL3516678 | 0.71 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL5513295 | 0.69 | ADORA2A (0.35) | LMNAPI4KB | |
| SCHEMBL170695 | 0.68 | ADORA2A (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219448-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | Myriad Pharmaceuticals, Inc. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009065035-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | MYRIAD GENETICS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |