Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542630 | 0.96 | LMNA (0.62) | LMNAGRIN2CALDH1A1NPSR1POLB | |
| SCHEMBL8546477 | 0.88 | LMNA (0.51) | LMNAGRIN2CALDH1A1NPSR1KMT2A | |
| SCHEMBL8544144 | 0.82 | LMNA (0.53) | LMNANPSR1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL7305217 | 0.80 | LMNA (0.72) | LMNAALDH1A1NPSR1POLBGAA | |
| SCHEMBL7302805 | 0.79 | LMNA (0.71) | LMNAALDH1A1NPSR1POLBGAA | |
| SCHEMBL7299161 | 0.79 | LMNA (0.71) | LMNAALDH1A1NPSR1POLBGAA | |
| SCHEMBL7311376 | 0.78 | LMNA (0.54) | LMNA | |
| SCHEMBL7304698 | 0.75 | LMNA (0.47) | LMNAPOLBL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL7301526 | 0.75 | LMNA (0.62) | LMNAGRIN2CALDH1A1NPSR1POLB | |
| SCHEMBL7304570 | 0.74 | LMNA (0.61) | LMNAGRIN2CALDH1A1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614893-B1 | Benzoxazine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1998-05-27 | — | — | EP | disclosed |
| US-5447928-A | Antiischemic agents and nervous system disorders | SYNTHELABO (FR) | 1995-09-05 | — | — | US | disclosed |
| EP-0614893-A1 | Benzoazine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |