Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FURIN | P09958 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549928 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRFURINALOX12ACACB | |
| SCHEMBL8549921 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRFURINALOX12ACACB | |
| SCHEMBL8549917 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRFURINALOX12ACACB | |
| SCHEMBL8551311 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRFURINALOX12ACACB | |
| Formamide SCHEMBL8545672 | 0.74 | PARP15 (0.51) | PARP10ACACB | |
| SCHEMBL25192665 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TSHRALOX12ACACBHRH3 | |
| SCHEMBL16902888 | 0.74 | FURIN (0.56) | ALDH1A1TSHRFURINPARP10ALOX12 | |
| Formamide SCHEMBL8550226 | 0.73 | THRB (0.48) | ALDH1A1TSHR | |
| SCHEMBL8546020 | 0.71 | FURIN (0.51) | ALDH1A1TSHRFURINPARP10FFAR4 | |
| SCHEMBL8544280 | 0.70 | FURIN (0.52) | FURINPARP10FFAR4BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |