Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544650 | 0.86 | PARP1 (0.42) | PLAURAB9AALDH1A1PARP1PARP15 | |
| SCHEMBL8538122 | 0.76 | MMP1 (0.40) | CYP1A2PLAURAB9ANPC1ALDH1A1 | |
| SCHEMBL8542589 | 0.73 | KMT2A (0.43) | CYP1A2RAB9ANPC1ALDH1A1PARP1 | |
| SCHEMBL8541231 | 0.71 | PARP1 (0.40) | CYP1A2RAB9ANPC1ALDH1A1PARP1 | |
| SCHEMBL5354517 | 0.71 | L3MBTL1 (0.60) | RAB9AALDH1A1MAPTKCNK3KCNK9 | |
| SCHEMBL1185244 | 0.70 | KMT2A (0.58) | NR1H4RAB9ANPC1PARP1PARP15 | |
| SCHEMBL8544672 | 0.70 | KMT2A (0.37) | CYP1A2PLAURAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3839558 | 0.69 | KMT2A (0.57) | NR1H4RAB9ANPC1PARP1PARP15 | |
| Hydrochloric Acid SCHEMBL29568124 | 0.69 | KMT2A (0.57) | NR1H4RAB9ANPC1PARP1PARP15 | |
| SCHEMBL895690 | 0.69 | MEN1 (0.63) | ALDH1A1PARP1PARP15PARP14PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |