Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538927 | 0.92 | MEN1 (0.49) | ALDH1A1GAATSHRHTTGFER | |
| SCHEMBL8543376 | 0.92 | AURKA (0.46) | ALDH1A1GAATSHRHTTGFER | |
| SCHEMBL8543854 | 0.91 | ALDH1A1 (0.54) | ALDH1A1GAATSHRHTTGFER | |
| SCHEMBL8541706 | 0.91 | MEN1 (0.43) | ALDH1A1GAATSHRHTTGFER | |
| SCHEMBL8537546 | 0.85 | MEN1 (0.51) | ALDH1A1GAAGFERHSD17B10MEN1 | |
| SCHEMBL8543931 | 0.83 | BRD4 (0.46) | ALDH1A1POLB | |
| SCHEMBL8543318 | 0.81 | MEN1 (0.45) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8539181 | 0.75 | HTR6 (0.56) | MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8538700 | 0.75 | TBXAS1 (0.55) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8539179 | 0.74 | POLB (0.47) | ALDH1A1GAATSHRHTTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |