Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546687 | 0.87 | MAPK1 (0.57) | MEN1KMT2AFKBP1AALDH1A1CYP3A4 | |
| SCHEMBL8544838 | 0.85 | P2RX7 (0.56) | P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL8544266 | 0.84 | HPGD (0.54) | P2RX7MEN1KMT2AFKBP1AALDH1A1 | |
| SCHEMBL8549537 | 0.80 | EPHX2 (0.56) | FKBP1AALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL8544795 | 0.80 | FKBP1A (0.59) | FKBP1AALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL8545060 | 0.79 | KMT2A (0.46) | P2RX7MEN1KMT2AFKBP1AALDH1A1 | |
| SCHEMBL8543599 | 0.78 | EPHX1 (0.54) | KMT2AFKBP1AALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL8543317 | 0.77 | F2 (0.58) | FKBP1AALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL7452551 | 0.76 | FKBP1A (0.60) | FKBP1AALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL2441194 | 0.76 | FKBP1A (0.60) | FKBP1AALDH1A1CYP3A4CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |