Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549494 | 0.89 | ALDH1A1 (0.56) | HPGDCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL8549705 | 0.87 | PKM (0.54) | PKMALDH1A1SMN1; SMN2F2EPHX2 | |
| SCHEMBL8546687 | 0.85 | MAPK1 (0.57) | CYP3A4CYP2C9PKMCYP2C19FKBP1A | |
| SCHEMBL8543196 | 0.85 | HSD11B1 (0.62) | PKMALDH1A1SMN1; SMN2P2RX7MEN1 | |
| SCHEMBL8544843 | 0.84 | P2RX7 (0.59) | HPGDCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL8543051 | 0.83 | RAB9A (0.56) | HPGDCYP2C19ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8544264 | 0.83 | HSD11B1 (0.46) | HPGDFKBP1AALDH1A1MAPK1P2RX7 | |
| SCHEMBL8544257 | 0.83 | HSD11B1 (0.46) | HPGDFKBP1AALDH1A1MAPK1P2RX7 | |
| SCHEMBL8544795 | 0.82 | FKBP1A (0.59) | HPGDCYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL8549405 | 0.80 | CYP3A4 (0.52) | CYP3A4CYP2C9PKMCYP2C19FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |