Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546685 | 0.86 | HSD11B1 (0.54) | ALDH1A1HSD11B1EPHX1 | |
| SCHEMBL8546679 | 0.86 | HSD11B1 (0.54) | ALDH1A1HSD11B1EPHX1 | |
| SCHEMBL8544843 | 0.85 | P2RX7 (0.59) | P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL8544264 | 0.83 | HSD11B1 (0.46) | P2RX7ALDH1A1HSD11B1LMNAEPHX1 | |
| SCHEMBL8544257 | 0.83 | HSD11B1 (0.46) | P2RX7ALDH1A1HSD11B1LMNAEPHX1 | |
| SCHEMBL8544571 | 0.81 | HTT (0.49) | ALDH1A1 | |
| SCHEMBL8549977 | 0.81 | HSD11B1 (0.44) | P2RX7ALDH1A1HSD11B1EPHX1 | |
| SCHEMBL8549532 | 0.80 | KMT2A (0.53) | HSD11B1 | |
| SCHEMBL8549527 | 0.80 | KMT2A (0.53) | HSD11B1 | |
| SCHEMBL8543273 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |