Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518684 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HTTL3MBTL1CYP1A2POLB | |
| SCHEMBL8550168 | 0.78 | KMT2A (0.54) | ALDH1A1HTTL3MBTL1POLBNPSR1 | |
| SCHEMBL8545816 | 0.77 | KMT2A (0.46) | ALDH1A1HTTL3MBTL1CYP1A2POLB | |
| Hydrochloric Acid SCHEMBL8546948 | 0.77 | KMT2A (0.53) | ALDH1A1HTTL3MBTL1POLBNPSR1 | |
| SCHEMBL9530939 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP1A2SMN1; SMN2TSHRTNFRSF1A | |
| Hydrochloric Acid SCHEMBL8550542 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HTTL3MBTL1CYP1A2POLB | |
| SCHEMBL8816107 | 0.76 | L3MBTL1 (0.52) | ALDH1A1HTTL3MBTL1CYP1A2POLB | |
| SCHEMBL8549831 | 0.76 | LMNA (0.53) | ALDH1A1HTTL3MBTL1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL8812987 | 0.75 | L3MBTL1 (0.51) | ALDH1A1HTTL3MBTL1CYP1A2POLB | |
| Hydrochloric Acid SCHEMBL8548333 | 0.75 | LMNA (0.52) | ALDH1A1HTTL3MBTL1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |